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Why Multi-Drug Resistance Occurs in India

Multi-drug resistance isn’t written into anyone’s genes. It’s something humans keep causing, one wrong antibiotic dose at a time.

An antibiotic sensitivity test on a petri dish culture
An antibiotic sensitivity test, used to check whether bacteria have become resistant to specific antibiotics. Photo by Dr Graham Beards, via Wikimedia Commons. Licensed CC BY-SA 4.0.
📑 Contents
🏛️ Must Know
What Actually Causes Multi-Drug Resistance in India
  • Not Genetic Predisposition A person’s genetic predisposition is not a reason microbial pathogens develop multi-drug resistance; that’s an unrelated human trait.
  • Incorrect Antibiotic Dosing Taking incorrect doses of antibiotics genuinely is a real reason for multi-drug resistance developing.
  • Antibiotics in Livestock Using antibiotics in livestock farming genuinely is a real reason multi-drug resistance spreads.
  • Multiple Chronic Diseases People with multiple chronic diseases genuinely are more exposed to repeated antibiotic use, a real contributing reason.
  • Correct Answer Statements 2, 3, and 4 are correct. The answer is 2, 3 and 4.

Good to Know

📘 Good to Know
How These Human Behaviours Actually Drive Resistance
  • Incomplete Courses Select for Survivors Stopping antibiotics early or taking too little lets the hardiest bacteria survive and multiply, passing resistance genes onward.
  • Livestock Use Is Widespread Antibiotics are routinely given to healthy livestock to promote growth, creating constant selection pressure for resistant bacteria.
  • Resistant Genes Can Spread Between Bacteria Bacteria can transfer resistance genes to each other directly. Resistance developed in one setting can spread to unrelated infections this way.
📝 Previous Year Questions
UPSC CSP 2019 — What Actually Causes Multi-Drug Resistance

Test Yourself

1. Which of the following is NOT a reason microbial pathogens develop multi-drug resistance?
2. Which of the following are the reasons for the occurrence of multi-drug resistance in microbial pathogens in India? 1. Genetic predisposition of some people 2. Taking incorrect doses of antibiotics to cure diseases 3. Using antibiotics in livestock farming 4. Multiple chronic diseases in some people
3. Why does stopping an antibiotic course early or taking too little contribute to resistance?
4. How does routine antibiotic use in healthy livestock contribute to antimicrobial resistance?
5. Which global health body has named antimicrobial resistance one of the top public health threats?

 

Great to Know

🌟 Great to Know
Why India Faces This Problem Acutely
  • Over-the-Counter Access Antibiotics remain widely available without prescription in many parts of India, encouraging self-medication and incomplete courses.
  • A Global Health Priority The World Health Organization has named antimicrobial resistance one of the top global public health threats.
  • Connects to Other PYQ Facts This same resistance theme also underlies UPSC questions on Hepatitis B and C and other infectious diseases.

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